GLP-1 injections

How are GLP-1 injections administered?

GLP-1 injections like Zepbound and Mounjaro are injected subcutaneously in the abdomen, thigh, or the back of the upper arm, with injection sites rotated each dose [1][2]. Both are given once weekly at any time of day, with or without meals [1][2]. If a dose is missed, it can be given within 4 days; beyond that, the missed dose is skipped and the regular weekly schedule resumed [1][2].

What forms do GLP-1 injection pens and vials come in?

Zepbound is supplied as a single-dose pen, a single-dose vial, a single-patient-use KwikPen delivering four doses, or a multi-dose vial with four doses [1]. Mounjaro is supplied as a single-dose pen or single-dose vial at strengths from 2.5 mg to 15 mg per 0.5 mL [2]. An injection pen must never be shared between patients, even with a new needle [2].

Is every GLP-1 medication an injection?

Not necessarily: tirzepatide, the medicine in Zepbound and Mounjaro, has no FDA-approved oral form in these facts, so both of its brands are given only by injection [1][2]. Compounded tirzepatide, sold outside the FDA-approved brands, is not reviewed by the FDA for safety, effectiveness, or quality before it reaches a patient [3].