Ozempic

What is Ozempic indicated for?

Ozempic injection is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes [1]. It's also indicated to reduce the risk of major adverse cardiovascular events in adults with type 2 diabetes and established cardiovascular disease, and to reduce the risk of sustained kidney function decline, end-stage kidney disease, and cardiovascular death in adults with type 2 diabetes and chronic kidney disease [1]. All three indications apply to adults only [1].

How is Ozempic dosed?

Ozempic injection starts at 0.25 mg once weekly [1]. After 4 weeks, the dosage increases to 0.5 mg weekly, and may rise further to 1 mg and then 2 mg weekly if more glycemic control is needed, with 2 mg as the maximum recommended dosage [1]. It's injected subcutaneously in the abdomen, thigh, or upper arm [1].

Is there an oral version of Ozempic?

Yes: a second dosage form, an Ozempic oral tablet, is published on DailyMed under a label shared with Rybelsus [2]. The Ozempic tablet is taken orally once daily and comes in 1.5 mg, 4 mg, and 9 mg strengths, which differ from Rybelsus's 3 mg, 7 mg, and 14 mg strengths on that same label, so the two brands aren't interchangeable milligram-for-milligram [2]. See Rybelsus for the other brand on that label.